SCHEMBL20165

SCHEMBL20165

CCc1c[nH]c(=O)nc1N

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 3/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ PNP P00491 2/20 0.31
▸ ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356920 0.86 BACE1 (0.39) DHFRPNP
SCHEMBL5491579 0.83 TLR8 (0.44) —
SCHEMBL1665906 0.83 PNP (0.31) PNP
SCHEMBL356158 0.82 TLR8 (0.45) —
SCHEMBL2512344 0.82 SUMO1 (0.36) PNP
SCHEMBL26506 0.82 SUMO1 (0.36) PNP
SCHEMBL2938692 0.82 PNP (0.31) PNP
SCHEMBL10728725 0.81 LMNA (0.46) GAA
SCHEMBL2828998 0.81 — —
SCHEMBL29512549 0.80 SUMO1 (0.36) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2061 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 — — WO claimed
EP-4717779-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TriLink BioTechnologies, LLC (US) 2026-04-01 — — EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 — — CN claimed
US-11549111-B2 Composition for suppressing inflammation KYOTO UNIVERSITY (JP) 2023-01-10 — — US claimed
US-10174372-B2 Preservation of information related to genomic DNA methylation ILLUMINA, INC. (US) 2019-01-08 — — US claimed
US-20170260581-A1 PRESERVATION OF INFORMATION RELATED TO GENOMIC DNA METHYLATION ILLUMINA, INC. 2017-09-14 — — US claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 — — US claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 — — US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 — — US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 — — US claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 — — EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 — — EP claimed
US-5208221-A Nucleotides and intermediates for herpes virus or leukemia virus BRISTOL-MYERS SQUIBB COMPANY (US) 1993-05-04 — — US claimed
EP-0525106-A4 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS — 1993-04-21 — — EP claimed
EP-0525106-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1993-02-03 — — EP claimed
WO-1993000099-A2 USE OF PYRIMIDINE AND PURINE NUCLEOSIDES FOR THE PROPHYLAXIS AND/OR TREATMENT OF INFECTIONS CAUSED BY ADENOVIRUSES Max-Delbrück-Centrum für Molekulare Medizin (DE) 1993-01-07 — — WO claimed
US-5128458-A 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents SOUTHERN RESEARCH INSTITUTE (US) 1992-07-07 — — US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 — — WO claimed
WO-1991016333-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1991-10-31 — — WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 — — EP claimed
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