SCHEMBL20165

SCHEMBL20165

CCc1c[nH]c(=O)nc1N

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHFR P00374 3/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
PNP P00491 2/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356920 0.86 BACE1 (0.39) DHFRPNP
SCHEMBL5491579 0.83 TLR8 (0.44)
SCHEMBL1665906 0.83 PNP (0.31) PNP
SCHEMBL356158 0.82 TLR8 (0.45)
SCHEMBL2512344 0.82 SUMO1 (0.36) PNP
SCHEMBL2938692 0.82 PNP (0.31) PNP
SCHEMBL26506 0.82 SUMO1 (0.36) PNP
SCHEMBL10728725 0.81 LMNA (0.46) GAA
SCHEMBL2828998 0.81
SCHEMBL29512549 0.80 SUMO1 (0.36) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2061 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
EP-4717779-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TriLink BioTechnologies, LLC (US) 2026-04-01 EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-11549111-B2 Composition for suppressing inflammation KYOTO UNIVERSITY (JP) 2023-01-10 US claimed
US-10174372-B2 Preservation of information related to genomic DNA methylation ILLUMINA, INC. (US) 2019-01-08 US claimed
US-20170260581-A1 PRESERVATION OF INFORMATION RELATED TO GENOMIC DNA METHYLATION ILLUMINA, INC. 2017-09-14 US claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
US-5208221-A Nucleotides and intermediates for herpes virus or leukemia virus BRISTOL-MYERS SQUIBB COMPANY (US) 1993-05-04 US claimed
EP-0525106-A4 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS 1993-04-21 EP claimed
EP-0525106-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1993-02-03 EP claimed
WO-1993000099-A2 USE OF PYRIMIDINE AND PURINE NUCLEOSIDES FOR THE PROPHYLAXIS AND/OR TREATMENT OF INFECTIONS CAUSED BY ADENOVIRUSES Max-Delbrück-Centrum für Molekulare Medizin (DE) 1993-01-07 WO claimed
US-5128458-A 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents SOUTHERN RESEARCH INSTITUTE (US) 1992-07-07 US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
WO-1991016333-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1991-10-31 WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed