SCHEMBL1665906

SCHEMBL1665906

NCc1c[nH]c(=O)nc1N

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 0.31
MPO P05164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29261403 0.87 ALDH1A1 (0.31)
SCHEMBL20165 0.83 DHFR (0.33) PNP
SCHEMBL2512344 0.82 SUMO1 (0.36) PNP
SCHEMBL26506 0.82 SUMO1 (0.36) PNP
SCHEMBL7597747 0.81 MPO (0.38) MPO
SCHEMBL29512549 0.80 SUMO1 (0.36) PNP
SCHEMBL7607407 0.80 MPO (0.40) MPO
SCHEMBL18132313 0.79
SCHEMBL20744797 0.79
SCHEMBL542389 0.79 PNP (0.37) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP VICO THERAPEUTICS B.V. (NL) 2026-05-28 US disclosed
WO-2026099473-A1 OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE VICO THERAPEUTICS B.V. (NL) 2026-05-15 WO disclosed
EP-4728071-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASE ProQR Therapeutics II B.V. (NL) 2026-04-22 EP disclosed
EP-4713459-A2 ANTI-VISTA ANTIBODY RNA OR NUCLEIC ACID CONJUGATES (ARCS OR ANCS), COMPOSITIONS CONTAINING, AND THERAPEUTIC USE THEREOF LIFORDI IMMUNOTHERAPEUTICS, INC. (US) 2026-03-25 EP disclosed
EP-4702143-A2 COMPOSITIONS AND METHODS FOR TREATING STXBP1 DISORDERS BioMarin Pharmaceutical Inc. (US) 2026-03-04 EP disclosed
EP-4702144-A1 ANTISENSE OLIGOMERS FOR TREATMENT OF CHRONIC KIDNEY DISEASE Sarepta Therapeutics, Inc. (US) 2026-03-04 EP disclosed
US-20260048076-A1 METHODS FOR DECREASING OR INHIBITING HUMAN L1 RETROTRANSPOSON RNA AND COMPOSITIONS FOR USE THEREIN ALTOS LABS, INC. (US) 2026-02-19 US disclosed
EP-4015631-B1 NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES GLAXOSMITHKLINE IP DEV LTD (GB) 2026-02-18 EP disclosed
EP-4688143-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF LIVER DISEASE ProQR Therapeutics II B.V. (NL) 2026-02-11 EP disclosed
EP-4689110-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS ProQR Therapeutics II B.V. (NL) 2026-02-11 EP disclosed
US-20130035237-A1 Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing AGILENT TECHNOLOGIES, INC. 2013-02-07 US disclosed
WO-2012144906-A1 NEW COMPOUNDS FOR TREATING, DELAYING AND/OR PREVENTING A HUMAN GENETIC DISORDER SUCH AS MYOTONIC DYSTROPHY TYPE 1 (DM1) PROSENSA TECHNOLOGIES B.V. (NL) 2012-10-26 WO disclosed
US-8148503-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2012-04-03 US disclosed
EP-2307565-A2 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING Lasergen, Inc. (US) 2011-04-13 EP disclosed
US-20100041041-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2010-02-18 US disclosed
WO-2009152353-A2 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2009-12-17 WO disclosed
US-4879377-A Nucleoside process BRISTOL-MYERS COMPANY (US) 1989-11-07 US disclosed
EP-0145978-B1 NUCLEOSIDE PROCESS Bristol-Myers Company (US) 1989-04-19 EP disclosed
US-4625020-A Nucleoside process BRISTOL-MYERS COMPANY (US) 1986-11-25 US disclosed
EP-0145978-A2 Nucleoside process Bristol-Myers Company (US) 1985-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041041-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING UNG, NT5C2, NT5E PNP 15/4885MPO 1577/4885
US-20130035237-A1 Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing UNG, NT5C2, NT5E PNP 15/4885MPO 1577/4885
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP APP, PSEN2, PSEN1 PNP 243/4885MPO 4076/4885
US-20260048076-A1 METHODS FOR DECREASING OR INHIBITING HUMAN L1 RETROTRANSPOSON RNA AND COMPOSITIONS FOR USE THEREIN POT1, FBL, HNRNPA1 PNP 182/4885MPO 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.