SCHEMBL20165469

SCHEMBL20165469

CCOC(=O)CC(C)N(C)C(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 4/20 0.47
ACHE P22303 4/20 0.47
NPY5R Q15761 2/20 0.47
ALDH1A1 P00352 4/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28308247 0.84 NPY5R (0.52) BCHEACHENPY5RALDH1A1TDP1
SCHEMBL21522848 0.82 ABCB1 (0.56) ALDH1A1TSHRMAPTL3MBTL1
SCHEMBL5370760 0.82 NPY5R (0.57) BCHEACHENPY5RALDH1A1TDP1
SCHEMBL21522945 0.81 ALDH1A1 (0.40) ACHEALDH1A1TSHRMAPTTDP1
SCHEMBL4924150 0.80 NPY5R (0.51) BCHEACHENPY5RALDH1A1TDP1
SCHEMBL20180238 0.78 MGAM (0.41) ALDH1A1TSHRTDP1
SCHEMBL19105330 0.76 TSHR (0.50) ALDH1A1TSHRMAPTTDP1ATM
SCHEMBL21522920 0.76 GAA (0.43) ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL3475218 0.75 NPY5R (0.59) BCHEACHENPY5RALDH1A1MAPT
SCHEMBL18353137 0.75 BCHE (0.47) BCHEACHENPY5RALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541857-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2020-09-09 EP disclosed
US-10654946-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2020-05-19 US disclosed
US-20190330388-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-10-31 US disclosed
EP-3541857-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2019-09-25 EP disclosed
WO-2018091375-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 WO disclosed