Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28485852 | 0.87 | ATM (0.43) | L3MBTL1LMNATDP1ATMMAPT | |
| SCHEMBL21522836 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL20168886 | 0.81 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL20165469 | 0.81 | BCHE (0.47) | ALDH1A1L3MBTL1TSHRTDP1ATM | |
| SCHEMBL20165457 | 0.79 | GAA (0.37) | ALDH1A1POLBHSD17B10TSHRTDP1 | |
| SCHEMBL20165345 | 0.78 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL20166109 | 0.78 | LMNA (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL21522838 | 0.77 | MAPT (0.33) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL20165352 | 0.76 | CTSK (0.34) | — | |
| SCHEMBL21522901 | 0.75 | DNM1 (0.36) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2020-09-09 | — | — | EP | disclosed |
| US-10654946-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-05-19 | — | — | US | disclosed |
| US-20190330388-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-10-31 | — | — | US | disclosed |
| CN-109890852-A | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2019-06-14 | — | — | CN | disclosed |