Formic Acid

Formic Acid

SCHEMBL20165794

O=CO.O=COCCc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
AKR1B10 O60218 3/20 0.45
AKR1B1 P15121 3/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
FFAR1 O14842 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
KEAP1 Q14145 1/20 0.42
LMNA P02545 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28219713 0.94 CA1 (0.48) HCAR2TDP1AKR1B10AKR1B1CA1
SCHEMBL26583 0.94 CA1 (0.48) HCAR2TDP1AKR1B10AKR1B1CA1
Ammonia Solution, Strong SCHEMBL27697032 0.92 CA1 (0.47) HCAR2TDP1AKR1B10AKR1B1CA1
Phenyl Propionic Acid SCHEMBL30136446 0.85 KEAP1 (0.66) TDP1FFAR1KEAP1ALDH1A1MAPK1
Benzaldehyde SCHEMBL25344417 0.85 ALDH1A1 (0.52) HCAR2TDP1AKR1B10AKR1B1CA1
Acetophenone SCHEMBL25344165 0.83 KMT2A (0.50) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL4588882 0.82 CA1 (0.43) HCAR2TDP1AKR1B10AKR1B1CA1
SCHEMBL5534913 0.82 FFAR1 (0.48) FFAR1LMNATSHRIDO1HDAC2
SCHEMBL5535271 0.82 FFAR1 (0.61) CA1CA2CA9FFAR1NPC1
SCHEMBL27373 0.82 IDO1 (0.55) FFAR1LMNANPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541435-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE PERCEPTION OF FECAL MALODOUR Firmenich SA (CH) 2019-09-25 EP disclosed
WO-2018091686-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE PERCEPTION OF FECAL MALODOUR FIRMENICH SA (CH) 2018-05-24 WO disclosed