Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 10/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123426 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20165874 | 0.76 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3SCN9A | |
| SCHEMBL20165493 | 0.75 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL20165881 | 0.71 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3HTR1AGRIN1 | |
| SCHEMBL24180233 | 0.71 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3HTR1AGRIN1 | |
| SCHEMBL20176375 | 0.71 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL20165896 | 0.71 | RBP4 (0.41) | SLC6A2SLC6A4SLC6A3GRIN1GRIN2B | |
| SCHEMBL9596400 | 0.71 | SCN9A (0.46) | SLC6A2SLC6A4SLC6A3SCN9A | |
| SCHEMBL3123418 | 0.70 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL22296699 | 0.70 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541784-B1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RES LABORATORIES SWEDEN AB (SE) | 2023-09-13 | — | — | EP | disclosed |
| EP-3541784-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | Integrative Research Laboratories Sweden AB (SE) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091687-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2018-05-24 | — | — | WO | disclosed |