SCHEMBL20166031

SCHEMBL20166031

CCCC1CC=C(c2ccc3c(oc4c(F)c(C(F)(F)F)ccc43)c2F)CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367504 0.90
SCHEMBL24231718 0.90
SCHEMBL20179335 0.87
SCHEMBL20165749 0.87
SCHEMBL20165522 0.85
SCHEMBL20597166 0.84 RORC (0.30) RORC
SCHEMBL22122632 0.84 PIM1 (0.31)
SCHEMBL20179295 0.83 PDE3B (0.31)
SCHEMBL21655179 0.82
SCHEMBL20179400 0.81 PDE3B (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109554181-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2023-10-31 CN disclosed
CN-110023457-B Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2023-08-18 CN disclosed
US-11655417-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-05-23 US disclosed
US-11060029-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
US-11060029-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
US-20200339882-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-10-29 US disclosed
EP-3730591-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-10-28 EP disclosed
EP-3541892-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
EP-3541892-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
US-10774263-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2020-09-15 US disclosed
EP-3541892-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2019-09-25 EP disclosed
CN-110023457-A Liquid crystal media and liquid crystal display comprising it 默克专利股份有限公司 2019-07-16 CN disclosed
WO-2019076899-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-04-25 WO disclosed
WO-2019076899-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-04-25 WO disclosed
US-20190093013-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-03-28 US disclosed
US-20190093013-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-03-28 US disclosed
EP-3460025-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2019-03-27 EP disclosed
EP-3460025-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2019-03-27 EP disclosed
WO-2018091489-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-05-24 WO disclosed
WO-2018091489-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-05-24 WO disclosed