SCHEMBL20179400

SCHEMBL20179400

Fc1c(C2=CCC(C3CC3)CC2)ccc2c1oc1c(F)c(C(F)(F)F)ccc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20179305 0.95 PDE3B (0.30) PDE3BPDE3A
SCHEMBL29367504 0.91
SCHEMBL24231718 0.91
SCHEMBL20179341 0.88
SCHEMBL20179295 0.86 PDE3B (0.31) PDE3BPDE3A
SCHEMBL20179401 0.85
SCHEMBL20179335 0.83
SCHEMBL20179333 0.83
SCHEMBL20614174 0.82
SCHEMBL20166031 0.81 RORC (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11060029-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-07-13 US disclosed
EP-3541892-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
WO-2018091489-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-05-24 WO disclosed