Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301745 | 0.81 | KDM4E (0.77) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL4739612 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL2929292 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL6918814 | 0.77 | TSHR (0.46) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL16616673 | 0.77 | KDM4E (0.72) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL18106131 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL27904206 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL16387742 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL11470029 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL30531237 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |