SCHEMBL20166488

SCHEMBL20166488

CC(C)(C)OC(=O)COc1cc(C(F)(F)F)ccc1CN1CCCC12CCN(C(=O)O)CC2

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.64
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20182533 0.93 MGLL (0.67) MGLL
SCHEMBL25804139 0.90 MGLL (0.58) MGLLFAAH
SCHEMBL20182525 0.88 MGLL (0.77) MGLL
SCHEMBL19582318 0.84 MGLL (0.65) MGLLFAAH
SCHEMBL29417700 0.84 MGLL (0.65) MGLLFAAH
SCHEMBL25802771 0.81 MGLL (0.51) MGLL
SCHEMBL20166137 0.81 MGLL (0.60) MGLLFAAH
SCHEMBL29446977 0.81 MGLL (0.60) MGLLFAAH
SCHEMBL20168832 0.80 MGLL (0.81) MGLL
SCHEMBL20182559 0.80 MGLL (0.61) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541820-A1 MAGL INHIBITORS Abide Therapeutics, Inc. (US) 2019-09-25 EP disclosed
WO-2018093949-A1 MAGL INHIBITORS ABIDE THERAPEUTICS, INC. (US) 2018-05-24 WO disclosed