SCHEMBL20182525

SCHEMBL20182525

CC(C)(C)OC(=O)N1CCC2(CCCN2Cc2ccc(C(F)(F)F)cc2OCC(=O)O)CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20182533 0.93 MGLL (0.67) MGLL
SCHEMBL19582318 0.91 MGLL (0.65) MGLL
SCHEMBL29417700 0.91 MGLL (0.65) MGLL
SCHEMBL20166137 0.88 MGLL (0.60) MGLL
SCHEMBL20166488 0.88 MGLL (0.64) MGLL
SCHEMBL29446977 0.88 MGLL (0.60) MGLL
SCHEMBL20166493 0.87 MGLL (1.00) MGLL
SCHEMBL20182559 0.86 MGLL (0.61) MGLL
SCHEMBL20182605 0.85 MGLL (0.56) MGLL
SCHEMBL19582699 0.85 MGLL (0.56) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093949-A1 MAGL INHIBITORS ABIDE THERAPEUTICS, INC. (US) 2018-05-24 WO disclosed