Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522472 | 1.00 | MAPT (0.58) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL22147373 | 0.84 | MAPT (0.66) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL5693165 | 0.84 | MAPT (0.62) | MAPTALDH1A1ALDH1A3LMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL20168195 | 0.83 | MAPT (0.64) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL2076697 | 0.83 | MAPT (0.64) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL5693187 | 0.77 | MAPT (0.69) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL27917040 | 0.76 | ALDH1A1 (0.76) | MAPTALDH1A1ALDH1A3LMNAKDM4E | |
| SCHEMBL1419188 | 0.75 | ALDH1A1 (1.00) | MAPTALDH1A1ALDH1A3LMNACYP1A2 | |
| SCHEMBL25166792 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1ALDH1A3LMNACYP1A2 | |
| SCHEMBL30231654 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1ALDH1A3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2020-06-25 | — | — | US | disclosed |
| EP-3541368-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093566-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | PUF60, PBRM1, PCBP1 | MAPT 1982/4885ALDH1A1 4268/4885ALDH1A3 2755/4885 |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | PUF60, PBRM1, PCBP1 | MAPT 1982/4885ALDH1A1 4268/4885ALDH1A3 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.