Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 20/20 | 0.66 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168517 | 0.93 | MGLL (0.68) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20168055 | 0.89 | MGLL (0.63) | MGLL | |
| SCHEMBL20168607 | 0.87 | MGLL (0.65) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20168794 | 0.81 | MGLL (0.44) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137005 | 0.79 | MGLL (1.00) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20168740 | 0.77 | MGLL (0.66) | MGLLABHD6 | |
| SCHEMBL20166773 | 0.75 | MGLL (0.46) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137118 | 0.73 | MGLL (1.00) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137128 | 0.72 | MGLL (1.00) | MGLLPLA2G7ABHD6 | |
| SCHEMBL15094825 | 0.71 | MGLL (0.55) | MGLLPLA2G7ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |