Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 6/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168794 | 0.94 | MGLL (0.44) | MGLLUBE2MDCUN1D1PLA2G7ABHD6 | |
| SCHEMBL20168756 | 0.86 | MGLL (0.43) | MGLLCETPUBE2MDCUN1D1PLA2G7 | |
| SCHEMBL20137052 | 0.83 | MGLL (0.67) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20168517 | 0.82 | MGLL (0.68) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20166173 | 0.81 | MGLL (0.39) | MGLL | |
| SCHEMBL20151845 | 0.76 | MGLL (0.59) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137060 | 0.76 | MGLL (0.41) | MGLLCETPALDH1A1 | |
| SCHEMBL29561179 | 0.76 | MGLL (0.65) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20137074 | 0.76 | MGLL (0.65) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20167994 | 0.75 | MGLL (0.66) | MGLLPLA2G7ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |