Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137059 | 0.90 | MGLL (0.56) | MGLLALDH1A1ABHD6MEN1KMT2A | |
| SCHEMBL29561177 | 0.80 | MGLL (0.59) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137131 | 0.80 | MGLL (0.59) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20137102 | 0.78 | MGLL (0.77) | MGLLABHD6CYP2D6PLA2G7 | |
| SCHEMBL20570097 | 0.77 | MGLL (0.48) | MGLLABHD6MEN1KMT2ACYP2D6 | |
| SCHEMBL29562122 | 0.76 | MGLL (0.50) | MGLLABHD6MEN1KMT2ACYP2D6 | |
| SCHEMBL20136990 | 0.76 | MGLL (0.50) | MGLLABHD6MEN1KMT2ACYP2D6 | |
| SCHEMBL18064839 | 0.76 | ALDH1A1 (0.47) | MGLLALDH1A1ABHD6MEN1KMT2A | |
| SCHEMBL20769592 | 0.76 | MGLL (0.48) | MGLL | |
| SCHEMBL20503399 | 0.72 | MGLL (0.50) | MGLLABHD6MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |