Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017155 | 0.83 | ALOX15 (0.45) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL4666170 | 0.82 | ALOX15 (0.47) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL11295860 | 0.81 | EPHX1 (0.48) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL27674000 | 0.81 | ALOX15 (0.46) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL6130279 | 0.81 | IDO1 (0.56) | IDO1MEN1KMT2A | |
| SCHEMBL15547599 | 0.80 | ALOX15 (0.55) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL2928329 | 0.79 | ALOX15 (0.45) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL27993666 | 0.78 | ALOX15 (0.44) | ALOX15ELANEMEN1KMT2AADRB2 | |
| SCHEMBL31112414 | 0.78 | CXCL8 (0.53) | ALOX15ELANEMEN1KMT2A | |
| Bromide SCHEMBL16050020 | 0.78 | ALOX15 (0.53) | ALOX15ELANEMEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |