Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.68 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21577999 | 1.00 | FOLH1 (0.68) | FOLH1ANPEPENPEP | |
| SCHEMBL14508892 | 1.00 | FOLH1 (0.68) | FOLH1ANPEPENPEP | |
| SCHEMBL20179250 | 0.92 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL20168741 | 0.92 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL20179265 | 0.92 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL15247509 | 0.84 | CYP1A2 (0.63) | FOLH1 | |
| SCHEMBL12418042 | 0.84 | CYP1A2 (0.63) | FOLH1 | |
| SCHEMBL21578000 | 0.83 | FOLH1 (0.50) | FOLH1ANPEPENPEP | |
| SCHEMBL20168665 | 0.83 | FOLH1 (0.56) | FOLH1ANPEPENPEP | |
| SCHEMBL21570560 | 0.83 | FOLH1 (0.56) | FOLH1ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |