Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570560 | 1.00 | FOLH1 (0.56) | FOLH1SLC7A5ANPEPENPEPMRGPRX4 | |
| SCHEMBL20168766 | 0.94 | FOLH1 (0.49) | FOLH1SLC7A5 | |
| SCHEMBL21570577 | 0.94 | FOLH1 (0.49) | FOLH1SLC7A5 | |
| SCHEMBL20179248 | 0.91 | SLC7A5 (0.56) | FOLH1SLC7A5 | |
| SCHEMBL20179262 | 0.85 | SLC7A5 (0.49) | FOLH1SLC7A5 | |
| SCHEMBL21577999 | 0.83 | FOLH1 (0.68) | FOLH1ANPEPENPEP | |
| SCHEMBL20168567 | 0.83 | FOLH1 (0.68) | FOLH1ANPEPENPEP | |
| SCHEMBL14508892 | 0.83 | FOLH1 (0.68) | FOLH1ANPEPENPEP | |
| SCHEMBL20168300 | 0.81 | FOLH1 (0.57) | FOLH1SLC7A5 | |
| SCHEMBL23833858 | 0.81 | REN (0.44) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |