Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165471 | 0.90 | KDM4C (0.41) | KDM4CKDM4APHF8KDM2ACA12 | |
| SCHEMBL14229142 | 0.85 | MMP1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL25063454 | 0.83 | KDM4C (0.38) | KDM4CKDM4APHF8KDM2ACA12 | |
| SCHEMBL23846674 | 0.82 | GGPS1 (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL20165511 | 0.81 | AKR1B1 (0.47) | KDM4CPHF8CA12CA1CA9 | |
| SCHEMBL18388303 | 0.81 | CA12 (0.41) | CA12CA1CA2CA9TSHR | |
| SCHEMBL10087929 | 0.80 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12763775 | 0.77 | CA12 (0.43) | CA12CA1CA2CA9TSHR | |
| SCHEMBL14200270 | 0.75 | CA12 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14229151 | 0.73 | MMP1 (0.42) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091375-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | WO | disclosed |