Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26304040 | 0.87 | BACE1 (0.50) | BACE1SCN9AGRM5 | |
| SCHEMBL13655235 | 0.85 | SCN9A (0.62) | PTPN1PTPN11PTPN6BACE1AURKA | |
| SCHEMBL6885895 | 0.74 | PTPN1 (0.64) | PTPN1PTPN11PTPN6BACE1NPC1 | |
| SCHEMBL7483325 | 0.73 | CYP2A6 (0.53) | BACE1NPC1RAB9ASMN1; SMN2GSK3B | |
| SCHEMBL13655269 | 0.72 | SCN9A (0.59) | BACE1SCN9AKIT | |
| SCHEMBL23812448 | 0.71 | SCN9A (0.63) | PTPN1PTPN11SCN9ANPC1RAB9A | |
| SCHEMBL23812447 | 0.70 | SCN9A (0.62) | AURKASCN9AMAOB | |
| SCHEMBL23326698 | 0.70 | NQO2 (0.70) | PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL677476 | 0.69 | MEN1 (0.67) | PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23352870 | 0.68 | TRPV1 (0.67) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |