Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.64 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888524 | 0.87 | CCNA2 (0.53) | PTPN1PTPN11PTPN6BACE1NPC1 | |
| SCHEMBL6883824 | 0.85 | KMT2A (0.53) | PTPN1PTPN11PTPN6BACE1KCNQ3 | |
| SCHEMBL15707591 | 0.82 | BACE1 (0.44) | PTPN1PTPN11PTPN6BACE1P4HTM | |
| SCHEMBL26094468 | 0.82 | BACE1 (0.61) | BACE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31660405 | 0.82 | BACE1 (0.61) | BACE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6885464 | 0.80 | ROCK2 (0.58) | BACE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20425348 | 0.78 | SCN2A (0.67) | P4HTMNPC1RAB9AKMT2APOLB | |
| SCHEMBL6027251 | 0.77 | KMT2A (0.53) | BACE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6026031 | 0.77 | MEN1 (0.52) | PTPN1NPC1RAB9APTPN2MEN1 | |
| SCHEMBL10684470 | 0.76 | PTPN1 (0.88) | PTPN1PTPN11PTPN6BACE1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | AVANIR PHARMACEUTICALS | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | ICOS, TSLP, IKZF3 | PTPN1 2513/4885PTPN11 3097/4885PTPN6 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.