Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169325 | 0.89 | DGAT1 (0.47) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169368 | 0.88 | DGAT1 (0.46) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169380 | 0.88 | DGAT1 (0.46) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169324 | 0.87 | DGAT1 (0.45) | DGAT1PTGS2PTGS1 | |
| SCHEMBL15293927 | 0.87 | DGAT1 (0.60) | DGAT1PTGS2PTGS1BRD4MGAM | |
| SCHEMBL17772387 | 0.84 | DGAT1 (0.43) | DGAT1PTGS2 | |
| SCHEMBL20169321 | 0.83 | DGAT1 (0.56) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169395 | 0.81 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL20169393 | 0.81 | DGAT1 (0.47) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169365 | 0.80 | DGAT1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |