Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887561 | 0.90 | ALDH1A1 (0.39) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL30887186 | 0.86 | MAPT (0.38) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15229841 | 0.85 | MAPT (0.37) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15229838 | 0.85 | MAPT (0.37) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL887528 | 0.85 | HTT (0.39) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15885937 | 0.82 | ALDH1A1 (0.35) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL30887129 | 0.82 | MAPT (0.36) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15469249 | 0.82 | MAPT (0.36) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL13252790 | 0.81 | RECQL (0.42) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15693769 | 0.81 | MAPT (0.35) | MAPTKMT2APKMALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10007165-B2 | Electrophoretic fluids | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-9977309-B2 | Electrophoretic fluid | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |