SCHEMBL887561

SCHEMBL887561

CCN(CC)c1cc(NC(C)=O)c(N=Nc2c(C#N)cc([N+](=O)[O-])cc2C#N)cc1OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
MAPT P10636 5/20 0.39
RECQL P46063 3/20 0.39
POLB P06746 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
UBA2 Q9UBT2 1/20 0.39
KMT2A Q03164 2/20 0.39
PKM P14618 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.35
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15229841 0.90 MAPT (0.37) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL15229838 0.90 MAPT (0.37) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL20169558 0.90 MAPT (0.40) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL15885937 0.90 ALDH1A1 (0.35) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL30887186 0.89 MAPT (0.38) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL15693769 0.89 MAPT (0.35) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL887528 0.88 HTT (0.39) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL887611 0.86 ALDH1A1 (0.38) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL15469249 0.84 MAPT (0.36) ALDH1A1MAPTRECQLPOLBKDM4E
SCHEMBL30887129 0.84 MAPT (0.36) ALDH1A1MAPTRECQLPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3434764-B1 FABRIC AND HOME CARE PRODUCTS PROCTER & GAMBLE (US) 2026-04-08 EP disclosed
US-12338416-B2 Fabric and home care products with cold water protease THE PROCTER & GAMBLE COMPANY (US) 2025-06-24 US disclosed
EP-4159833-A2 FABRIC AND HOME CARE PRODUCTS The Procter & Gamble Company (US) 2023-04-05 EP disclosed
US-8067177-B2 Amplification methods EPOCH BIOSCIENCES, INC. (US) 2011-11-29 US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-20110027780-A1 AMPLIFICATION METHODS ELITECHGROUP MDX LLC 2011-02-03 US disclosed
US-7759126-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis ELITECH HOLDING B.V. (NL) 2010-07-20 US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 US disclosed
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND EPOCH BIOSCIENCES, INC. (US) 2008-11-27 US disclosed
US-20080248474-A1 AMPLIFICATION METHODS EPOCH BIOSCIENCES, INC (US) 2008-10-09 US disclosed
US-20080248474-A1 AMPLIFICATION METHODS EPOCH BIOSCIENCES, INC (US) 2008-10-09 US disclosed
US-7381818-B2 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof EPOCH BIOSCIENCES, INC. (US) 2008-06-03 US disclosed
US-7319022-B1 Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe EPOCH BIOSCIENCES, INC. (US) 2008-01-15 US disclosed
US-7319022-B1 Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe EPOCH BIOSCIENCES, INC. (US) 2008-01-15 US disclosed
US-7205105-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-04-17 US disclosed
US-7205105-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-04-17 US disclosed
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-01-04 US disclosed
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND SSBP1, DDB1, DNA2 ALDH1A1 3164/4885MAPT 3770/4885RECQL 1205/4885
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS DDX5, DDX21, DCLRE1B ALDH1A1 2211/4885MAPT 4706/4885RECQL 81/4885
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis RNGTT, DCLRE1B, CNBP ALDH1A1 3606/4885MAPT 4694/4885RECQL 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.