Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20501048 | 0.88 | SCN9A (0.64) | SCN9ASCN3AAOC3MASP2LTA4H | |
| SCHEMBL28364786 | 0.86 | SCN9A (0.62) | SCN9ASCN3AAOC3MASP2LTA4H | |
| SCHEMBL13655206 | 0.80 | SCN3A (0.69) | SCN9ASCN3AMASP2MEN1KMT2A | |
| SCHEMBL13663135 | 0.78 | SCN3A (0.69) | SCN9ASCN3AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20501157 | 0.78 | SCN9A (0.57) | SCN9ASCN3AMASP2 | |
| SCHEMBL23812448 | 0.78 | SCN9A (0.63) | SCN9ASCN3AHTTSMN1; SMN2MASP2 | |
| SCHEMBL13655245 | 0.78 | SCN9A (0.54) | SCN9ASCN3AAOC3MASP2MEN1 | |
| SCHEMBL13663134 | 0.78 | RAB9A (0.55) | SCN9ASCN3ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23812447 | 0.77 | SCN9A (0.62) | SCN9ASCN3AMASP2LTA4H | |
| SCHEMBL16866191 | 0.76 | SCN9A (0.52) | SCN9ASCN3AAOC3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |