Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.60 |
| ▸ | MASP2 | O00187 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20501157 | 0.89 | SCN9A (0.57) | SCN9ASCN3AMASP2KDRSCN4A | |
| SCHEMBL28364786 | 0.89 | SCN9A (0.62) | SCN9ASCN3AMASP2LTA4HMAPT | |
| SCHEMBL20169736 | 0.88 | SCN9A (0.61) | SCN9ASCN3AMASP2LTA4HMAPT | |
| SCHEMBL13655206 | 0.83 | SCN3A (0.69) | SCN9ASCN3AMASP2MAPTRAB9A | |
| SCHEMBL20501030 | 0.82 | SCN9A (0.61) | SCN9ASCN3AMASP2MAPTKDR | |
| SCHEMBL20501076 | 0.82 | SCN9A (0.61) | SCN9ASCN3AMASP2MAPTRAB9A | |
| SCHEMBL24176844 | 0.81 | SCN9A (0.47) | SCN9ASCN3AMASP2MAPTAOC3 | |
| SCHEMBL13663135 | 0.81 | SCN3A (0.69) | SCN9ASCN3AMASP2RAB9AKDR | |
| SCHEMBL23812448 | 0.81 | SCN9A (0.63) | SCN9ASCN3AMASP2LTA4HMAPT | |
| SCHEMBL13655245 | 0.81 | SCN9A (0.54) | SCN9ASCN3AMASP2LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
| WO-2018169752-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | SCN9A 4811/4885SCN3A 4795/4885MASP2 1274/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | SCN9A 4811/4885SCN3A 4795/4885MASP2 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.