Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169876 | 1.00 | S1PR5 (0.39) | S1PR5KDM1APIN1MRGPRX4XDH | |
| SCHEMBL3668993 | 0.90 | PIN1 (0.39) | PIN1XDHL3MBTL1CA2CA5A | |
| SCHEMBL3669336 | 0.90 | PIN1 (0.39) | PIN1XDHL3MBTL1CA2CA5A | |
| SCHEMBL17523255 | 0.89 | MRGPRX4 (0.43) | S1PR5KDM1AMRGPRX4XDHFFAR1 | |
| SCHEMBL16160599 | 0.81 | FAAH (0.36) | KDM1AXDHPPARD | |
| SCHEMBL20169882 | 0.80 | CYP3A4 (0.47) | S1PR5KDM1ACA2CA5A | |
| SCHEMBL20169866 | 0.80 | CYP3A4 (0.47) | S1PR5KDM1ACA2CA5A | |
| SCHEMBL20169865 | 0.80 | CYP3A4 (0.47) | S1PR5KDM1ACA2CA5A | |
| SCHEMBL20169883 | 0.80 | CYP3A4 (0.47) | S1PR5KDM1ACA2CA5A | |
| SCHEMBL14408042 | 0.80 | APP (0.39) | PIN1L3MBTL1CA2CA5ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975869-B2 | Analogues of epicatechin and related polyphenols | SPHAERA PHARMA PVT. LTD. (IN) | 2018-05-22 | — | — | US | disclosed |