Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | USP9X | Q93008 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162455 | 0.90 | SCN9A (0.31) | SCN9A | |
| SCHEMBL16718972 | 0.90 | SCN9A (0.31) | SCN9A | |
| SCHEMBL20170477 | 0.85 | SCN9A (0.31) | ALOX5APFEN1SCN9ADRD2DRD3 | |
| SCHEMBL16730881 | 0.83 | SCN9A (0.36) | MEN1KMT2ASCN9A | |
| SCHEMBL16730893 | 0.82 | SCN9A (0.36) | MEN1KMT2ASCN9A | |
| SCHEMBL20170511 | 0.82 | SCN9A (0.36) | MEN1KMT2ASCN9A | |
| SCHEMBL20170497 | 0.79 | SCN9A (0.38) | SCN9A | |
| SCHEMBL16730885 | 0.79 | SCN9A (0.38) | SCN9A | |
| SCHEMBL18430859 | 0.75 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL16719019 | 0.75 | SCN9A (0.31) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068391-B1 | ARYL LINKED IMIDAZOLE AND TRIAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG | MERCK SHARP & DOHME (US) | 2018-05-23 | — | — | EP | disclosed |