SCHEMBL2017045

SCHEMBL2017045

NC(=S)S.[Cu].c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.50
MAOB P27338 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
TAAR1 Q96RJ0 2/20 0.48
CYP2A6 P11509 1/20 0.48
HTR2A P28223 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
NOS1 P29475 1/20 0.47
HTR3A P46098 1/20 0.47
FFAR1 O14842 1/20 0.45
CTSL P07711 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702198 0.98 MAOA (0.52) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL7889408 0.95 MAOA (0.50) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL17685698 0.95 MAOA (0.50) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL7584903 0.95 MAOA (0.50) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL422836 0.95 MAOA (0.50) MAOAMAOBSMN1; SMN2NPC1RAB9A
Ammonia Solution, Strong SCHEMBL23878420 0.95 MAOA (0.50) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL10597986 0.85 MAOA (0.54) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL8731548 0.83 FFAR1 (0.58) MAOAMAOBSMN1; SMN2TAAR1CYP2A6
SCHEMBL700765 0.83 CA12 (0.61) MAOAMAOBSMN1; SMN2NPC1RAB9A
SCHEMBL23878392 0.81 CA12 (0.59) MAOAMAOBSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444114-A Application of copper dibenzyl dithiocarbamate medicament to treatment of triple negative breast cancer 吴超君 2021-09-28 CN claimed
CN-113631647-B Sealant rubber composition for inner surface of tire and sealant coated tire 住友橡胶工业株式会社 2023-12-08 CN disclosed
CN-113444114-A Application of copper dibenzyl dithiocarbamate medicament to treatment of triple negative breast cancer 吴超君 2021-09-28 CN disclosed
CN-113444114-A Application of copper dibenzyl dithiocarbamate medicament to treatment of triple negative breast cancer 吴超君 2021-09-28 CN disclosed
CN-113444114-A Application of copper dibenzyl dithiocarbamate medicament to treatment of triple negative breast cancer 吴超君 2021-09-28 CN disclosed
CN-107428211-B Tyre for vehicle wheels 株式会社普利司通 2020-04-10 CN disclosed
CN-107428212-B Tyre for vehicle wheels 株式会社普利司通 2020-03-31 CN disclosed
US-8835566-B2 Rubber composition for vulcanization DAISO CO., LTD. (JP) 2014-09-16 US disclosed
EP-2083048-B1 RUBBER COMPOSITION FOR VULCANIZATION DAISO CO LTD (JP) 2013-01-02 EP disclosed
US-20110160344-A1 RUBBER COMPOSITION FOR VULCANIZATION Daisco Co. Ltd (JP) 2011-06-30 US disclosed
EP-2083048-A1 RUBBER COMPOSITION FOR VULCANIZATION DAISO CO., LTD. (JP) 2009-07-29 EP disclosed
US-20050070649-A1 Low VOC primer for roofing and waterproofing membranes WACHOVIA BANK, NATIONAL ASSOCIATION AS ADMINISTRATIVE AGENT 2005-03-31 US disclosed
US-RE37683-E1 WATERPROOFING, HERMETIC SEALING ADCO PRODUCTS, INC. 2002-04-30 US disclosed
US-6297324-B1 CURED RUBBER ADHESIVE TAPE FOR JOINING SHEETS OF EPDM RUBBER ROOFING, BLEND OF AN EPDM, A HALOGENATED BUTYL RUBBER OR HALOGENATED METHYLSTYRENE-ISOBUTYLENE COPLYMER, POLYISOBUTYLENE, AND TACKIFIER OF POLYBUTENE AND/OR A PHENOLIC ADCO PRODUCTS, INC. 2001-10-02 US disclosed
US-6106941-A Adhesive system ADCO PRODUCTS, INC. (US) 2000-08-22 US disclosed
WO-2000006662-A1 ADHESIVE SYSTEM FOR ADHERING POLAR TO NON-POLAR SURFACES ADCO PRODUCTS, INC. (US) 2000-02-10 WO disclosed
US-5387160-A A vulcanized belt is made of hydrogenated acrylonitrile-butadiene rubber, sulfur and a copper dithiocarbamates; tensile strength, elongation, durability MITSUBOSHI BELTING LTD. (JP) 1995-02-07 US disclosed
US-5242727-A Cured adhesive containing a rubber polymer blend, a tackifier resin and an accelerator/cure packages ADCO PRODUCTS, INC. (US) 1993-09-07 US disclosed
US-5234987-A Blend of halogenated copolymer of isobutylene and p-methylstyrene, thermoplastic rubber and tackifier ADCO PRODUCTS, INC. (US) 1993-08-10 US disclosed