Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18736433 | 1.00 | PKM (0.41) | PKMALDH1A1MAPTHPGDVSIR | |
| SCHEMBL16561722 | 1.00 | PKM (0.41) | PKMALDH1A1MAPTHPGDVSIR | |
| SCHEMBL19412603 | 0.89 | PKM (0.40) | PKMALDH1A1MAPTHPGDVSIR | |
| SCHEMBL16561751 | 0.79 | PKM (0.38) | PKMALDH1A1VSIRCD274PDCD1LG2 | |
| SCHEMBL18735670 | 0.76 | VSIR (0.48) | PKMVSIRCD274PDCD1LG2 | |
| SCHEMBL16557028 | 0.76 | VSIR (0.48) | PKMVSIRCD274PDCD1LG2 | |
| SCHEMBL19412601 | 0.75 | CD274 (0.50) | PKMMAPTVSIRCD274PDCD1LG2 | |
| SCHEMBL18736434 | 0.75 | CD274 (0.61) | PKMALDH1A1MAPTVSIRCD274 | |
| SCHEMBL16561723 | 0.75 | CD274 (0.61) | PKMALDH1A1MAPTVSIRCD274 | |
| SCHEMBL18736597 | 0.74 | CD274 (0.54) | PKMALDH1A1VSIRCD274PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041828-B1 | 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-05-23 | — | — | EP | disclosed |