Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170756 | 0.78 | TRPV1 (0.34) | TRPV1ALOX5BCHE | |
| SCHEMBL18473570 | 0.73 | GAA (0.32) | — | |
| SCHEMBL21202074 | 0.70 | GAA (0.47) | TRPV1 | |
| SCHEMBL20170851 | 0.68 | GAA (0.34) | — | |
| SCHEMBL22058061 | 0.65 | GAA (0.41) | — | |
| SCHEMBL12646160 | 0.63 | OPRM1 (0.48) | — | |
| SCHEMBL22058059 | 0.63 | OPRM1 (0.48) | — | |
| SCHEMBL20170594 | 0.63 | OPRM1 (0.33) | TRPV1 | |
| SCHEMBL20170689 | 0.60 | GAA (0.36) | — | |
| SCHEMBL21091301 | 0.60 | GAA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |