Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170759 | 0.96 | OPRM1 (0.52) | OPRM1OPRD1OPRK1SLC18A3 | |
| SCHEMBL20170615 | 0.88 | OPRM1 (0.52) | OPRM1OPRD1OPRK1LMNACYP1A2 | |
| SCHEMBL20170658 | 0.85 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170816 | 0.85 | OPRM1 (0.39) | OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL20170815 | 0.85 | OPRM1 (0.39) | OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL20170741 | 0.84 | OPRM1 (0.51) | OPRM1OPRD1OPRK1LMNACYP1A2 | |
| SCHEMBL20170791 | 0.84 | OPRM1 (0.51) | OPRM1OPRD1OPRK1LMNACYP1A2 | |
| SCHEMBL20170824 | 0.82 | OPRM1 (0.42) | OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL20170838 | 0.82 | OPRM1 (0.42) | OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL20170817 | 0.82 | OPRM1 (0.42) | OPRM1OPRD1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |