Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170759 | 0.87 | OPRM1 (0.52) | OPRM1OPRK1OPRD1MRGPRX2 | |
| SCHEMBL20170651 | 0.85 | OPRM1 (0.50) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170777 | 0.84 | OPRM1 (0.39) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170845 | 0.84 | OPRM1 (0.39) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170721 | 0.82 | OPRD1 (0.43) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170679 | 0.82 | OPRD1 (0.43) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170828 | 0.78 | OPRM1 (0.49) | OPRM1OPRK1OPRD1 | |
| SCHEMBL13575428 | 0.76 | OPRM1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL13506887 | 0.76 | OPRM1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL20170741 | 0.74 | OPRM1 (0.51) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |