Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18473438 | 0.84 | HCRTR1 (0.41) | HCRTR1LMNAOPRM1 | |
| SCHEMBL13972294 | 0.84 | HCRTR1 (0.41) | HCRTR1LMNAOPRM1 | |
| SCHEMBL13972295 | 0.84 | HCRTR1 (0.41) | HCRTR1LMNAOPRM1 | |
| SCHEMBL12826658 | 0.77 | OPRM1 (0.51) | HCRTR1LMNAOPRM1 | |
| SCHEMBL20170600 | 0.73 | OPRM1 (0.39) | MTNR1AMTNR1BLMNAMAPTOPRM1 | |
| SCHEMBL20170645 | 0.73 | OPRM1 (0.39) | MTNR1AMTNR1BLMNAMAPTOPRM1 | |
| SCHEMBL10223357 | 0.70 | HCRTR1 (0.43) | HCRTR1OPRM1 | |
| SCHEMBL20170648 | 0.68 | OPRM1 (0.62) | MTNR1AMTNR1BLMNAOPRM1 | |
| SCHEMBL12826660 | 0.68 | OPRM1 (0.38) | LMNAMAPTOPRM1 | |
| SCHEMBL13431185 | 0.66 | HTR1A (0.32) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |