Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576210 | 0.88 | ALDH1A1 (0.68) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL29935885 | 0.87 | CYP1A2 (0.55) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL9156343 | 0.87 | CYP1A2 (0.55) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL885156 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL11192972 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL4521046 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HPGDKMT2AGAAHTT | |
| Hydrochloric Acid SCHEMBL11157053 | 0.85 | CYP1A2 (0.53) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL935059 | 0.84 | HPGD (0.54) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL1244426 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL27682450 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673347-B1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-08-19 | — | — | EP | claimed |
| JP-2007507447-A | — | — | 2007-03-29 | — | — | JP | claimed |
| US-7166587-B2 | Carbamic acid alkyl ester derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-23 | — | — | US | claimed |
| EP-1673347-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. Hoffman-la Roche AG (CH) | 2006-06-28 | — | — | EP | claimed |
| WO-2005040126-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. HOFFMAN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | claimed |
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | HOFFMAN-LA ROCHE INC. | 2005-04-07 | — | — | US | claimed |
| EP-4145995-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CJB Applied Technologies, LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| WO-2021226566-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CJB APPLIED TECHNOLOGIES, LLC (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-3709804-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CJB Applied Technologies, LLC (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-1673347-B1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-08-19 | — | — | EP | disclosed |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| US-7166587-B2 | Carbamic acid alkyl ester derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-23 | — | — | US | disclosed |
| EP-1673347-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. Hoffman-la Roche AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | HOFFMAN-LA ROCHE INC. | 2005-04-07 | — | — | US | disclosed |
| CN-1087335-A | Substituted benzyl carbamates with herbicidal properties | CIBA GEIGY AG (CH) | 1994-06-01 | — | — | CN | disclosed |
| CN-1004353-B | Process for preparing N-methyl carbamates | 埃尼凯姆·辛泰希公司 | 1989-05-31 | — | — | CN | disclosed |
| EP-0298419-A2 | A protein partial degradation product, process for preparing it and its use | Katayama Chemical Works Co., Ltd. (JP) | 1989-01-11 | — | — | EP | disclosed |
| CN-85109417-A | The preparation method of N-methyl carbamate class | — | 1986-12-03 | — | — | CN | disclosed |
| US-4319018-A | IN ACID CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-03-09 | — | — | US | disclosed |
| EP-0031385-A1 | PROCESS FOR PREPARING POLYMETHYLENEPOLYPHENYL POLYCARBAMATE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | BCHE, CHRM1, ADCY7 | ALDH1A1 1434/4885HPGD 4445/4885KMT2A 2212/4885 |
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | ALDH1A1 574/4885HPGD 703/4885KMT2A 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.