Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.57 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503669 | 0.88 | HPGD (0.79) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL30780061 | 0.87 | HPGD (0.77) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL1568387 | 0.87 | HPGD (0.77) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL19630528 | 0.87 | HPGD (0.77) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL2017132 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL28646195 | 0.84 | HPGD (0.72) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL28643598 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL29200012 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL30474251 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL10425900 | 0.83 | HPGD (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864185-B | β -phosphonoenamine derivatives and process for their preparation | 苏州大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-105820061-A | Method for synthesizing N-alkylamide | 南京理工大学 | 2016-08-03 | — | — | CN | disclosed |
| US-8530506-B2 | Process for production of biphenyl derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-7589089-B2 | Inhibitors for GlyT-1 | HOFFMANN-LA ROCHE INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20080058331-A1 | Inhibitors for GlyT-1 | HOFFMANN-LA ROCHE INC. | 2008-03-06 | — | — | US | disclosed |
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058331-A1 | Inhibitors for GlyT-1 | GLRA1, SLC1A2, AGXT | ALDH1A1 867/4885HPGD 3821/4885KDM4E 1690/4885 |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | AGTR2, AGTR1, ACE | ALDH1A1 906/4885HPGD 1325/4885KDM4E 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.