Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 5/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864621 | 0.88 | USP9X (0.44) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL864620 | 0.88 | USP9X (0.44) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL10125036 | 0.84 | USP9X (0.40) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL865270 | 0.77 | SORT1 (0.48) | — | |
| SCHEMBL23818359 | 0.76 | CRBN (0.34) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL882298 | 0.73 | USP9X (0.55) | USP9XUCHL1USP5ALDH1A1FAAH | |
| SCHEMBL882300 | 0.72 | EGFR (0.46) | — | |
| SCHEMBL864756 | 0.72 | USP9X (0.68) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL864757 | 0.72 | USP9X (0.68) | USP9XUCHL1USP5CHRNB2CHRNA4 | |
| SCHEMBL10124900 | 0.71 | USP9X (0.78) | USP9XUCHL1USP5CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |