Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.59 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171645 | 0.92 | USP9X (0.60) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL20171559 | 0.92 | USP9X (0.56) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL20171600 | 0.91 | USP9X (0.68) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL20171582 | 0.90 | USP9X (0.58) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL20171596 | 0.89 | USP9X (0.56) | USP9XUSP24UCHL1USP5LTA4H | |
| SCHEMBL20171644 | 0.88 | USP9X (0.55) | USP9XUSP24UCHL1USP5LTA4H | |
| SCHEMBL20171591 | 0.86 | USP9X (0.54) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL20171649 | 0.84 | USP9X (0.49) | USP9XUSP24UCHL1USP5 | |
| SCHEMBL20171592 | 0.84 | USP9X (0.82) | USP9XUSP24UCHL1USP5KMT2A | |
| SCHEMBL882207 | 0.83 | USP9X (0.66) | USP9XUSP24UCHL1USP5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |