Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 8/20 | 0.55 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171645 | 0.95 | USP9X (0.60) | USP9XUSP24LTA4HUCHL1USP5 | |
| SCHEMBL20171596 | 0.90 | USP9X (0.56) | USP9XUSP24LTA4HUCHL1USP5 | |
| SCHEMBL20171516 | 0.88 | USP9X (0.59) | USP9XUSP24LTA4HUCHL1USP5 | |
| SCHEMBL20171582 | 0.87 | USP9X (0.58) | USP9XUSP24LTA4HUCHL1USP5 | |
| SCHEMBL20171591 | 0.83 | USP9X (0.54) | USP9XUSP24UCHL1USP5 | |
| SCHEMBL20171592 | 0.81 | USP9X (0.82) | USP9XUSP24UCHL1USP5ALDH1A1 | |
| SCHEMBL20171649 | 0.80 | USP9X (0.49) | USP9XUSP24UCHL1USP5 | |
| SCHEMBL20171559 | 0.80 | USP9X (0.56) | USP9XUSP24LTA4HUCHL1USP5 | |
| SCHEMBL20171593 | 0.79 | USP9X (0.48) | USP9XUSP24UCHL1USP5ALDH1A1 | |
| SCHEMBL20171600 | 0.79 | USP9X (0.68) | USP9XUSP24UCHL1USP5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |