Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.57 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.57 |
| ▸ | USP5 | P45974 | 1/20 | 0.57 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171646 | 0.93 | USP9X (0.58) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL864787 | 0.91 | USP9X (0.56) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL863498 | 0.91 | USP9X (0.71) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL863497 | 0.91 | USP9X (0.71) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL864788 | 0.91 | USP9X (0.56) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171608 | 0.88 | USP9X (0.59) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171570 | 0.86 | USP9X (0.50) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL863759 | 0.84 | USP9X (0.72) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL863758 | 0.84 | USP9X (0.72) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL882205 | 0.84 | USP9X (0.57) | USP9XUCHL1USP5USP24STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |