Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.59 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.59 |
| ▸ | USP5 | P45974 | 1/20 | 0.59 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882194 | 0.91 | USP9X (0.58) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171646 | 0.89 | USP9X (0.58) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171589 | 0.88 | USP9X (0.57) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL882298 | 0.86 | USP9X (0.55) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171593 | 0.86 | USP9X (0.48) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL20171592 | 0.84 | USP9X (0.82) | USP9XUCHL1USP5USP24KMT2A | |
| SCHEMBL20171600 | 0.84 | USP9X (0.68) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL882277 | 0.84 | USP9X (0.52) | USP9XUCHL1USP5USP24MAPT | |
| SCHEMBL10124917 | 0.83 | USP9X (0.61) | USP9XUCHL1USP5USP24STAT3 | |
| SCHEMBL10124903 | 0.83 | USP9X (0.61) | USP9XUCHL1USP5USP24STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |