Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171606 | 0.89 | USP9X (0.46) | USP9XUCHL1USP5USP24 | |
| SCHEMBL20171604 | 0.88 | USP9X (0.47) | USP9XUCHL1USP5USP24 | |
| SCHEMBL882305 | 0.83 | USP9X (0.54) | USP9XUCHL1USP5USP24 | |
| SCHEMBL882194 | 0.82 | USP9X (0.58) | USP9XUCHL1USP5USP24 | |
| SCHEMBL20171649 | 0.82 | USP9X (0.49) | USP9XUCHL1USP5USP24 | |
| SCHEMBL882205 | 0.81 | USP9X (0.57) | USP9XUCHL1USP5USP24 | |
| SCHEMBL882298 | 0.81 | USP9X (0.55) | USP9XUCHL1USP5USP24 | |
| SCHEMBL20171593 | 0.81 | USP9X (0.48) | USP9XUCHL1USP5USP24 | |
| SCHEMBL20171559 | 0.80 | USP9X (0.56) | USP9XUCHL1USP5USP24 | |
| SCHEMBL20171615 | 0.80 | USP9X (0.42) | USP9XUCHL1USP5USP24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |