Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171606 | 0.91 | USP9X (0.46) | USP9XUCHL1USP5USP24SLC2A1 | |
| SCHEMBL20171596 | 0.88 | USP9X (0.56) | USP9XUCHL1USP5USP24KDM4E | |
| SCHEMBL20171649 | 0.87 | USP9X (0.49) | USP9XUCHL1USP5USP24LMNA | |
| SCHEMBL20171608 | 0.86 | USP9X (0.59) | USP9XUCHL1USP5USP24LMNA | |
| SCHEMBL20171591 | 0.85 | USP9X (0.54) | USP9XUCHL1USP5USP24MAPT | |
| SCHEMBL20171645 | 0.83 | USP9X (0.60) | USP9XUCHL1USP5USP24ALDH1A1 | |
| SCHEMBL882298 | 0.83 | USP9X (0.55) | USP9XUCHL1USP5USP24ALDH1A1 | |
| SCHEMBL20171516 | 0.82 | USP9X (0.59) | USP9XUCHL1USP5USP24KMT2A | |
| SCHEMBL20171582 | 0.82 | USP9X (0.58) | USP9XUCHL1USP5USP24LMNA | |
| SCHEMBL20171652 | 0.81 | USP9X (0.45) | USP9XUCHL1USP5USP24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |