Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979956 | 0.94 | ESR2 (0.47) | ESR2GRIA4USP30USP5HDAC6 | |
| SCHEMBL18503359 | 0.94 | ESR2 (0.47) | ESR2GRIA4USP30USP5HDAC6 | |
| SCHEMBL9979948 | 0.88 | ESR2 (0.52) | ESR2GRIA4USP30USP5HDAC6 | |
| SCHEMBL8767567 | 0.87 | HTR2A (0.39) | GRIA4USP30USP5HDAC6HCRTR2 | |
| SCHEMBL12975733 | 0.86 | ESR2 (0.41) | ESR2GRIA4USP30USP5HDAC6 | |
| SCHEMBL10043148 | 0.86 | ESR2 (0.41) | ESR2USP30USP5HDAC6HCRTR2 | |
| SCHEMBL10043337 | 0.86 | ESR2 (0.41) | ESR2USP30USP5HDAC6HCRTR2 | |
| SCHEMBL10043343 | 0.86 | ESR2 (0.41) | ESR2GRIA4USP30USP5HDAC6 | |
| SCHEMBL23366152 | 0.85 | HTR2A (0.38) | GRIA4USP30USP5HDAC6HCRTR2 | |
| SCHEMBL14525325 | 0.85 | HTR2A (0.38) | GRIA4USP30USP5HDAC6HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521401-A1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | Merck Patent GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3327102-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |
| EP-3323872-A1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |