Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | ACHE | P22303 | 5/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168286 | 0.89 | NPC1 (0.66) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL22024384 | 0.89 | ACHE (0.48) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL18773627 | 0.89 | NPC1 (0.57) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL18558980 | 0.88 | NPC1 (0.61) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL19624008 | 0.86 | NPC1 (0.56) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL18699560 | 0.86 | NPC1 (0.48) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL20172076 | 0.86 | RXFP1 (0.59) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL18869362 | 0.86 | NPC1 (0.56) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL21589213 | 0.85 | NPC1 (0.55) | NPC1RAB9ARXFP1MEN1MIF | |
| SCHEMBL18473063 | 0.85 | NPC1 (0.55) | NPC1RAB9ARXFP1MEN1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-12 | — | — | EP | disclosed |
| EP-3521401-B1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | MERCK PATENT GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |
| EP-3730591-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3521401-A1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | Merck Patent GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2019110458-A1 | LIQUID-CRYSTALLINE MEDIUM FOR USE IN A SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2019-06-13 | — | — | WO | disclosed |
| EP-3067406-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-3323872-A1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |