Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558980 | 0.90 | NPC1 (0.61) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19624008 | 0.88 | NPC1 (0.56) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18473063 | 0.87 | NPC1 (0.55) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20112835 | 0.87 | NPC1 (0.47) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2302972 | 0.86 | NPC1 (0.57) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9607860 | 0.86 | NPC1 (0.54) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20171778 | 0.86 | NPC1 (0.61) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18869362 | 0.86 | NPC1 (0.56) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21589213 | 0.85 | NPC1 (0.55) | RXFP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2168286 | 0.85 | NPC1 (0.66) | RXFP1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162875-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |