Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARG | P13631 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17546810 | 0.91 | BACE1 (0.49) | ELANEBACE1KMT2AATMLMNA | |
| SCHEMBL17485631 | 0.91 | ELANE (0.49) | ELANEBACE1KMT2AATMSLC6A9 | |
| SCHEMBL17546745 | 0.90 | ELANE (0.42) | ELANEBACE1KMT2AATMLMNA | |
| SCHEMBL24170583 | 0.90 | ELANE (0.42) | ELANEBACE1KMT2AATMSLC6A9 | |
| SCHEMBL22277289 | 0.90 | ELANE (0.43) | ELANEBACE1KMT2AATMLMNA | |
| SCHEMBL15834835 | 0.88 | ELANE (0.51) | ELANEKMT2AATMLMNAGAA | |
| SCHEMBL22083555 | 0.88 | BACE1 (0.41) | ELANEBACE1KMT2AATMSLC6A9 | |
| SCHEMBL22277288 | 0.86 | ELANE (0.41) | ELANEKMT2AATMLMNAGAA | |
| SCHEMBL24575151 | 0.85 | ELANE (0.55) | ELANEBACE1KMT2AATMSLC6A9 | |
| SCHEMBL22083044 | 0.84 | BACE1 (0.39) | ELANEBACE1KMT2AATMSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521401-A1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | Merck Patent GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3333243-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2018-06-13 | — | — | EP | disclosed |
| EP-3323872-A1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |