SCHEMBL22277288

SCHEMBL22277288

C=C(C)C(=O)Oc1ccc(-c2ccc(OC(=O)C(=C)CC)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
RARA P10276 1/20 0.36
RARB P10826 1/20 0.36
FFAR1 O14842 6/20 0.36
PPARD Q03181 4/20 0.36
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
FAAH O00519 1/20 0.34
ABCB1 P08183 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
FFAR4 Q5NUL3 3/20 0.33
CYP17A1 P05093 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ACLY P53396 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607907 0.91 ELANE (0.48) ELANEKMT2AATMRARARARB
SCHEMBL19824549 0.91 ELANE (0.48) ELANEKMT2AATMRARARARB
SCHEMBL19497304 0.90 ACLY (0.41) ELANEKMT2AATMRARARARB
SCHEMBL20998246 0.89 KMT2A (0.42) ELANEKMT2AATMRARARARB
SCHEMBL22277289 0.88 ELANE (0.43) ELANEKMT2AATMLMNAGAA
SCHEMBL22459243 0.88 ELANE (0.39) ELANEKMT2AATMRARARARB
SCHEMBL15834835 0.87 ELANE (0.51) ELANEKMT2AATMLMNAGAA
SCHEMBL20171780 0.86 ELANE (0.42) ELANEKMT2AATMRARARARB
SCHEMBL16789924 0.86 ELANE (0.38) ELANEKMT2AATMRARARARB
SCHEMBL16789920 0.86 ELANE (0.38) ELANEKMT2AATMRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254873-B2 Liquid crystal composition, liquid crystal display element and liquid crystal display SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL, CO., LTD. (CN) 2022-02-22 US disclosed
US-11242487-B2 Liquid crystal composition, liquid crystal display element and liquid crystal display SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2022-02-08 US disclosed
WO-2021134962-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY 石家庄诚志永华显示材料有限公司 2021-07-08 WO disclosed
US-20200239777-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-07-30 US disclosed
US-20200239779-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-07-30 US disclosed