Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385765 | 0.78 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL5385754 | 0.78 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL4035803 | 0.76 | KDM4E (0.56) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL5392736 | 0.75 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL5392742 | 0.75 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL1433137 | 0.74 | ALDH1A1 (0.57) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL17055696 | 0.73 | KDM4E (0.56) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL14594588 | 0.73 | ALDH1A1 (0.49) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL14594589 | 0.71 | KDM4E (0.47) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL536876 | 0.71 | KDM4E (0.53) | KDM4EMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622880-B3 | SUBSTITUTED DIHYDROCHINAZOLINES HAVING ANTIVIRAL PROPERTIES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |