Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463018 | 0.85 | KDM4E (0.51) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| SCHEMBL2462081 | 0.85 | KDM4E (0.51) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| SCHEMBL8876235 | 0.79 | KDM4E (0.58) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| Hydrochloric Acid SCHEMBL8876539 | 0.75 | KDM4E (0.51) | KDM4EGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL29658280 | 0.72 | DRD2 (0.56) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| Hydrochloric Acid SCHEMBL29461349 | 0.71 | DRD2 (0.55) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| Hydrochloric Acid SCHEMBL29461356 | 0.71 | DRD2 (0.55) | KDM4EGAAKMT2AALDH1A1DRD2 | |
| SCHEMBL12333837 | 0.70 | RECQL (0.44) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL24249397 | 0.69 | HSD11B1 (0.46) | GAAKMT2AALDH1A1MEN1PKM | |
| SCHEMBL19862764 | 0.69 | KMT2A (0.41) | KDM4EGAAKMT2AALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547696-B1 | FRAGMENTS OF THE PA SUBUNIT OF RNA DEPENDENT RNA POLYMERASE FROM PANDEMIC INFLUENZA VIRUS A 2009 H1N1, AND THEIR USE | EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL (DE) | 2018-05-23 | — | — | EP | disclosed |